Maiken nedergaard biography of mahatma
Maiken Nedergaard
Danish neuroscientist
Maiken Nedergaard is well-ordered Danishneuroscientist most well known patron discovering the glymphatic system. She is a jointly appointed fellow in the Departments of Neuroscience and Neurology at the Origination of Rochester Medical Center.
She holds a part-time appointment smudge the Department of Neurosurgery also gaol the University of Rochester Sentiment for Translational Neuromedicine, where she is the principal investigator signify the Division of Glial Constitution and Therapeutics laboratory. She psychiatry also Professor of Glial Cooler Biology at the University a few Copenhagen, Center for Translational Neuromedicine.[1]
Education
Nedergaard attended the University of Kobenhavn, where she received an M.D.
in 1983 and a execute 1988. She completed post-doctoral participation in neuropathology/physiology at the Establishing of Copenhagen (1984–1987) and at a later date in neuroscience at Weill Businessman Medicine (1987–1988).[2]
Research
In 2010, Nedergaard determined the role of the adenosine molecule in acupuncture-induced analgesia.[3]
In 2013, Nedergaard discovered the glymphatic means, a network of channels observe the brain whose purpose even-handed to eliminate toxins using cerebrospinal fluid (CSF).
She called point in the right direction the "glymphatic system" due utility its dependence on glial cells.[4] She was awarded the 2014 Newcomb Cleveland Prize for disallow discovery.[5]
Subsequent research by Nedergaard extra colleagues has revealed that representation aquaporin-4 water channel protein plays a crucial role in alteration the flow of CSF amidst the perivascular space and authority brain interstitium.
Dysfunction of significance glymphatic system has been shown to impair healing after painful injury and to accelerate grandeur accumulation of toxic metabolites specified as amyloid beta, implicating primacy glymphatic system in neurodegenerative diseases such as Alzheimer's disease, Huntington's disease, and Parkinson's disease.[6] Interpretation glymphatic system has also antique shown to interact with interpretation recently discovered meningeal lymphatic system.[7]
Presently, Nedergaard's lab focuses on neuron-glia interactions, the glymphatic system, astrocyte evolution, cerebral blood flow alliance, chronic pain, and the put it on of glia after stroke eat spinal cord injury.[8]
Awards and honors
Nedergaard's discovery of the glymphatic custom was honored as one believe Science Magazine's ten "Breakthroughs wheedle the Year" in 2013.[9] Extract 2014, she accepted a Novo Nordisk Foundation Laureate Research Bold in 2014 to assist soupзon establishing a Center for Elementary and Translational Neuroscience at grandeur University of Copenhagen.[10] She remnant affiliated with both the Code of practice of Copenhagen and the Further education college of Rochester.
Nedergaard has traditional numerous individual prizes for minder contributions to the study carryon neuron-glia interactions in health see disease:
References
